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Tell Us More About Your Lexus ES300. View all models

AutoZone carries hundreds of thousands of parts and accessories.

Select your Year, Make, Model and Engine to find those that fit your vehicle.

As one of the most luxurious sedans in its class, your Lexus ES300 tops the charts in style, safety and comfort. With its premium interior and sleek outer frame, you don't want to compromise with subpar parts. Installing AutoZone's premium Lexus ES300 thermostat today and keep your engine running at its optimal temperature.

Show of 24  Results
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  •  | Page 1 of 2 |  
  • Part Number: 7281-180
  • Warranty: 1 YR
  • Application: OE recommended temperature
  • Notes: 180 °F (82 °C)
    Engineered to permit continuous flow of coolant when overheating occurs.
  • Part Number: 7281-180
  • Warranty: 1 YR
  • Application: OE recommended temperature
  • Notes: 180 °F (82 °C)
    Engineered to permit continuous flow of coolant when overheating occurs.
  • Part Number: 7281-180
  • Warranty: 1 YR
  • Application: OE recommended temperature
  • Notes: 180 °F (82 °C)
    Engineered to permit continuous flow of coolant when overheating occurs.
  • Part Number: 7281-180
  • Warranty: 1 YR
  • Application: OE recommended temperature
  • Notes: 180 °F (82 °C)
    Engineered to permit continuous flow of coolant when overheating occurs.
  • Part Number: 7281-180
  • Warranty: 1 YR
  • Application: OE recommended temperature
  • Notes: 180 °F (82 °C)
    Engineered to permit continuous flow of coolant when overheating occurs.
  • Part Number: 7281-180
  • Warranty: 1 YR
  • Application: OE recommended temperature
  • Notes: 180 °F (82 °C)
    Engineered to permit continuous flow of coolant when overheating occurs.
  • Part Number: 7281-180
  • Warranty: 1 YR
  • Application: OE recommended temperature
  • Notes: 180 °F (82 °C)
    Engineered to permit continuous flow of coolant when overheating occurs.
  • Part Number: 7281-180
  • Warranty: 1 YR
  • Application: OE recommended temperature
  • Notes: 180 °F (82 °C)
    Engineered to permit continuous flow of coolant when overheating occurs.
  • Part Number: 4077
  • Warranty: 1 YR
  • Application: Alternate temperatures
  • Notes: 170 °F (77 °C)
  • Part Number: 4077
  • Warranty: 1 YR
  • Application: Alternate temperatures
  • Notes: 170 °F (77 °C)
  • Part Number: 15078
  • Warranty: 1 YR
  • Application: OE recommended temperature
  • Notes: 180 °F (82 °C)
  • Part Number: 4077
  • Warranty: 1 YR
  • Application: Alternate temperatures
  • Notes: 170 °F (77 °C)
  •  | Page 1 of 2 |  

The last thing that you want to worry about when heading out on your next road-trip is an overheated engine caused by a faulty thermostat. With our top-quality line of ES300 thermostats, you never have to worry about a hot, steamy engine. Our thermostat replacement for Lexus ES300 keeps your trusty engine cool and regulated right after install. Utilize our handy Loan-a-Tool program and Same Day Store Pickup (in most cases) option and get the thermostat installed and your car back on the road in no time. You can also order from us online and benefit from Free Shipping on any purchase of $75 or more.

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